The reasons for the problem to occur remain unknown for ages. Guillain-Barre syndrome first shows up after a certain period of time once the patient faces any respiratory or digestive tract infection. So, these are interconnected factors. The immune system is the target to suffer. A healthy system tries to destroy only the invading foreign bodies like viruses or infections; in the case of Guillain-Barre syndrome, the nervous system attack body’s native nerves. As a result, the brain stops receiving necessary signal. It leads to numbness or full paralysis.