The symptoms of this severe disease include breathlessness or running out of the air. Another common sign is an ongoing cough created by mucus. Sometimes, this cough, as well as other sounds coming out of the mouth, are supported by wheezing. It becomes too difficult for the patient to do every day physical exercises like jumping, running, or even simply walking. This disease progresses smoothly. Only if you notice slow deterioration, it can be a symptom. In many cases, the same problem is faced by the heavy smokers.