The specific signs depend on the personality of the patient. Some signals occur suddenly and disappear with time, just to appear later again. The patients who have schizophrenia regularly have a bad mood. They believe that everything in the world turns against them. They are also not easy going with people around. The idea-fix may destroy their brain. These people are rather sensitive, so they can overreact to the smallest problems, which usually leads to long-lasting depressions. Depression is a widespread phenomenon, but it’s important not to confuse it with melancholy or temporary bad mood.