Adapalene (Differin) is one more retinoid. Since 1997, the treatment is available in the US. If you’re looking for the first aid to fight the noninflammatory acne, it is one of the best options on the market. Adapalene gets rid of blackheads and/or whiteheads. It would be a great addition to the therapy with antibiotics to cope with the problem. The drug eliminates papules, pustules, cysts, and/or nodules. Take a prescription and buy Adapalene as a cream, lotion, or gel. Apply it once per day.