Blood in the urine. As we said before, your kidney and urinary system are connected. Problems with kidney cause not just bubbles and foam in your urine, but also blood. Yes, bloody urine sounds more serious than fatigue or bad mood and this symptom will lead you straight to the doctor. You should go to the hospital as soon as possible. Kidney disease may be not even the worse problem in this case. So do not waste your time as soon as you notice any blood signs in your urine.