Asymmetrical pain. Unlike rheumatoid arthritis, psoriatic arthritis is often characterized by asymmetric pain. There may be 1-3 joints be affected, for example, knee, elbow, and wrist, but their paired joints are not affected. Tiredness and lassitude. Psoriatic arthritis may not be treated easily. It requires a lot of time and patient care. Very often, patients feel weak, lack of vital energy, and poor appetite. The fight against the disease, of course, makes the body weaker and provokes uncontrollable fatigue. Consult with your doctor what methods will be most optimal and less energy-intensive for you.