Erythema nodosum disease progresses both internally and externally. It is possible to notice red lumps and rash in several damaged areas. As a rule, those are the lower extremities, especially knees. The lumps quickly become rather sensitive and cause itchy and painful feeling. The worst thing is that nodules can become rather large in short period, which makes this sort of skin’s rash even more troublesome.

Even when these lumps are gone, the bruised look will stay. They are usually burning/inflaming, especially when the disease reaches its peak. The cases of chronic erythema nodsum are known when the person suffers from the lumps and nodules periodically for the interval of several weeks up to several months. It is not necessary that a previous disease should have taken place.

Causes of erythema nodosum: bacterial infections, fungal infections, enteropathies, drugs, Behçet disease, sarcoidosis. Doctors name a streptococcal infection the most widespread source of the problem. At the same time, grown-ups suffer from the similar problem, known as sarcoidosis supported by the same infection which attacks childish organism. Tuberculosis is another famous predecessor of erythema nodosum. As for the fungal infections, it is important to recall Coccidioidomycosis.