Diagnosing Chronic Myeloid Leukemia:
Proper and timely diagnosis of CML is crucial for effective management. Healthcare professionals use a combination of methods to diagnose the condition, including:
Blood Tests: A complete blood count (CBC) helps assess the number and characteristics of blood cells, providing initial clues for further investigation.
Bone Marrow Aspiration and Biopsy: A sample of bone marrow is collected from the hipbone and examined under a microscope to confirm the presence of abnormal cells.
Cytogenetic Analysis: This test identifies the Philadelphia chromosome, a genetic abnormality characteristic of CML.
Molecular Tests: Polymerase chain reaction (PCR) and fluorescence in situ hybridization (FISH) detect specific genetic mutations associated with CML.
Medical Imaging: Imaging techniques like X-rays, CT scans, or ultrasounds help determine the extent of organ involvement and check for an enlarged spleen or liver.