Pain upon removal of pressure on the abdomen. One of the distinctive tests of appendicitis is when the physician palpates or presses down gently on the area of the abdomen over the appendix. In appendicitis, a patient will experience pain, not when the pressure is applied, but when the pressure is released, in an effect that the medical fraternity calls ‘rebound tenderness’. You should not attempt to do this yourself in the later stages of the condition, and even if you do this in the initial stages, you should not repeat it if you experience the effect once. It is a clear indicator of appendicitis, so if you experience it, consult your doctor immediately.