Acute and lasting pain in the bones is the most common sign that a person might be having a bone cancer. The patients define this type of pain as itching and burning like it is eating from inside. It does not usually last for several minutes – the patients are likely to suffer for an extended period of time. Often, the source of such pain comes from within a certain bone. Various tumors around the bone area create another threat. Various therapies like the one against cancer may cause this outcome too.