An official definition of Scleroderma states that it is an autoimmune disease associated with the connective tissues. It refers to the developments matched together. However, the level of complications and the signs are different for different people. Scleroderma is quite dangerous is it may influence various necessary parts of the organism. Those are human heart, kidneys, and lungs. To translate it directly, the disease means “hard skin.” The connective tissue starts increasing untypically. It impacts different organs.
It is impossible to name the main cause of Scleroderma accurately. Thanks to the numerous studies, it is possible to say that certain genes may take part in passing the predisposition to this disease. Another important factor to consider is the environment. In the end, the immune system activates. It harms the internal lining of the small blood vessels. Such activation also does damage to the tissues. A consequence is the appearance of a scar tissue as well as the storage of collagen, which is abnormal and not good at all.