Symptoms and Signs of Sepsis

Fever and temperature dysregulation are frequently described in sepsis. Reports note body temperatures exceeding 101°F (38.3°C) or, in some cases, falling below 96.8°F (36°C). Fluctuations in temperature during the course of illness are commonly accompanied by chills and shivering, which appear in many clinical summaries as associated systemic reactions.

A reduction in the volume and frequency of urination (oliguria) is often documented. This feature is discussed as a marker of altered kidney perfusion or function in systemic illness. In severe presentations, multiple organ systems can be affected, including kidneys, lungs, and liver. Descriptions emphasize that decreased urinary output is evaluated together with other sepsis indicators.

An increased heart rate and rapid breathing are frequently reported. Tachycardia reflects circulatory responses to systemic inflammation, while tachypnea accompanies metabolic and respiratory demands. These changes are associated with altered oxygen delivery and can coincide with a sensation of breathlessness during illness.

Gastrointestinal manifestations such as diarrhea may be present, particularly when sepsis follows enteric or intra-abdominal infection. Descriptions include watery stools and irregular bowel movements, sometimes accompanied by nausea, vomiting, or abdominal distension. Duration and intensity vary across individuals and underlying causes.

Cutaneous findings are described in some sepsis contexts. Rashes can appear as small red or violaceous spots and may reflect the infectious source or systemic responses. Distribution and warmth of affected areas are noted in examinations, while summaries emphasize that not all sepsis cases feature a rash and presentations differ by etiology.

Breathing difficulties are frequently mentioned as the condition progresses. Individuals describe a sense of chest tightness and effortful inhalation. Such respiratory complaints are discussed in relation to lung involvement, cardiovascular changes, or vascular tone alterations that accompany systemic inflammation.

Abdominal pain is included among reported features and may be acute or persistent. Early discomfort can be localized and later become more diffuse or intense. Activities that increase intra-abdominal pressure can accentuate pain. Descriptions link abdominal symptoms to gastrointestinal or intra-abdominal sources that may underlie sepsis in some cases.

Changes in mental status are described, including confusion, reduced attention, and disorganization. These findings are discussed as effects of systemic infection and altered perfusion on the central nervous system. Individuals may appear unfocused and have difficulty tracking events, with variability in prominence and timing.

Dizziness, lightheadedness, or a spinning sensation (vertigo) can occur during systemic illness. Educational materials relate these sensations to changes in blood pressure, cardiac output, and overall hydration status. Reports also mention associated fatigue and episodes of faintness in some individuals during acute phases.

Persistent weakness and tiredness are frequently recorded. Generalized muscle and joint discomfort are described alongside sleep disruption and reduced stamina. Overviews note that recovery trajectories vary, and individuals can report lingering fatigue during convalescence together with diffuse bodily aches and sleep difficulties.

Learn more about sepsis at Centers for Disease Control and Prevention.

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