Most of these symptoms are interrelated. An ongoing cough and shortness of breath, for instance, prevent the patient from having a healthy sleep at night. It results into the severe fatigue the next day. Sometimes, Sarcoidosis may cause problems with the skin. At least 20% of the patients reported this fact. For example, a red rash covers the body. Most of the time, the lower extremities get affected. Lesions form on the face.