Due to the unusual impotence of the girdle of shoulder and the pelvic muscles, patients may be riveted to a wheelchair or bed. The defeat of the muscles of the larynx and the upper parts of the esophagus leads to a violation of swallowing and regurgitation. The muscles of the lower and upper limbs and face are usually not affected. Skin eruptions usually have a dark color and erythematous character. Periorbital swelling of purple color is also a characteristic. Skin eruptions may slightly rise above the skin surface and be smooth or covered with scales.