A patient may notice a drop in the level of urination as well as its frequency. Do not confuse this sign with the acute kidney disease before you make sure. It should be accompanied by the other signs of sepsis to conclude. A serious form of sepsis can lead to the acute failure of numerous organs. Those are kidneys, lungs, and liver. Check the level of urinary output. It should not be below 400 ml. In case of sepsis, damage to the specific organ results in a stopped urine’s output.