Exhaustion. A feeling of extreme tiredness may be one of the less obvious symptoms of an infection of the bladder. This is important to know because, while some of the more known symptoms are pain while urinating and discolored urine, these symptoms may not always be present. It has been observed that sometimes when an older woman suffers a bladder infection, the only symptom she experiences is exhaustion. As exhaustion is a symptom of a large number of ailments, this can make diagnosing a bladder infection quite difficult in some cases.